Myanmar Health Sciences Research Journal


Archives   2018

Myanmar   Health   Sciences   Research   Journal

Volume   30,  Number   2

TITLE:   Effect of Different Room Temperatures on Breeding Performance of icr Strain Mice
AUTHOR:   Sandar Lin, Aye Win Oo, Htay Yee, Kyaw Kyaw Wai, Nyunt Nyunt1, Than Tint 1, Aye Aye Shwe1, Thida2 & Win Aung2
SOURCE:   Myanmar Health Sciences Research Journal, Vol. 30, No. 2, 2018
ABSTRACT:   Temperature is one of the environmental factors and the laboratory mice may have physiological changes because of the environmental temperature. Food and temperature availability have a strong interaction that influences the reproductive performance of female mice throughout the reproductive cycle. This study aimed to analyze the effect of different room temperatures in the housing room on breeding performance of icr mice. In this study, healthy 15 males and 45 females with 1:3 mating ratio of icr strain mice, weighing 25-30 gm, were used for breeding performance under different room temperatures; 18-22˚C, 23-25˚C and 26-32˚C conditions. The monitoring and evaluation were done during 21 days, from birth to weaning for each group. Fertility rate, delivery rate, litter size, birth weight, weaning rate, weaning weight and mortality rate were monitored at the first, the second and the third consecutive gestations. It was found that fertility rate 100%, delivery rate 100%, litter size 9, weaning rate 99.75% and mortality rate 0.24% in group one condition; fertility rate 100%, delivery rate 100%, litter size 7.67%, weaning rate 98.67% and mortality rate 1.32% in group two condition; fertility rate 71.11%, delivery rate 71.11%, litter size 5.33, weaning rate 80.63% and mortality rate 19.37% in group three condition; were found in the first, the second and the third gestations in this study. Birth weight 1.5±0.1 gm and weaning weight 9.5±0.1 gm were found in every room condition. The findings showed that high temperature has effect to lower growth rate and impaired fertility. It was found that the high temperature (26-32˚C) is not suitable for breeding performance and well-being of the animals.
SUBJECT HEADINGS:   Temperature, Reproductive performance, Mice
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar