Myanmar Health Sciences Research Journal
Volume 10, Number 3
TITLE: Correlation between immunofluorescence assay (IFA) positivity and malaria endemicity in Myanmar.
AUTHOR: Khin Saw Aye; Soe Soe; Queuche, F; Aung Htay
SOURCE: Myanmar Health Sciences Research Journal. 1998; 10(3): 139-142
ABSTRACT: Immunofluorescence assay (IFA) for intra-erythrocytic Plasmodium falciparum parasite was determined in all ages and both sexes of permanent inhabitants of 3 villages in Myanmar with differing malaria endemicity. According to the WHO criteria, malaria endemicity depends on the parasite positive rate and spleen rate and the 3 villages could be characterized as one village each of hypoendemicity, mesoendemicity and hyperendemicity. The prevalence of IFA positivity were 30% , 71% and 97% and the mean IFA titers were 800, 13,800 and 174,000 in the hypo, meso and hyperendemic villages respectively.. Thus, there is a good correlation between malaria endemicity and the IFA positivity and mean IFA titers. These data indicate that IFA assay can be used to assess malaria endemicity and applicable where proper epidemiological surveys especially in low and medium endemic areas are not possible.
SUBJECT HEADINGS: Fluorescent Antibody Technique. Malaria.