Myanmar Health Sciences Research Journal


Archives   2000

Myanmar   Health   Sciences   Research   Journal

Volume   12,  Number   1-3

TITLE:   Green pit viper (Trimeresurus erthrurus)bite in Myanmar: clinical features, venom antigen levels and development of Nature venom antibodies.
AUTHOR:   Tun Pe; Aye Aye Myint; Nu Nu Aung
SOURCE:   Myanmar Health Sciences Research Journal. 2000; 12(1-3): 1-6
ABSTRACT:   Green pit viper (Trimeresurus erythrurus) bite is common in Myanmar and only few bites have been reported. Clinical features, venom antigen levels and development of venom antibodies in four green pit viper bites were presented. Pain and local swelling started early after the bite and spread to involve more than half of the bitten limb in 2-3 days and subsided on 5 days after the bite. Incoagulability of blood was observed as early as 1.15 to 2.40 h after the bite. One systemic envenomed case presented with vomiting, abdominal colic, sweating, hypotension and shock. Thrombocytopenia, neutrophilic leucocytosis, anaemia and raised blood urea were present for a week. Initial venom antigen levels ranged from 47 to 103 ng/ml. Antigen clearance depends on "venom hours". The pattern of antibody response following the bite was short lived in nature. Monospecific Russell's viper antivenom has no effect on correcting coagulation defect.
SUBJECT HEADINGS:   Viper Venoms. Snake Bites. Antigens.
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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar