Myanmar Health Sciences Research Journal
Volume 25, Number 3
TITLE: Determination of Antibiotics Residues in Fish and Prawn.
AUTHOR: Khin Chit; Ni Lar Aung; Min Wun; Moe Moe Aye; Kyi Kyi Myint; Thiri Aung; Mya Mya Moe
SOURCE: Myanmar Health Sciences Research Journal. 2013; 25(3): 196-201
ABSTRACT: Food is the principle factor for the existence of human life. Antibiotics are drugs of natural or synthetic origin that have the capacity to kill or inhibit the growth of microorganisms. The use and misuse of antibiotics in animals consumed as food has increased around 2001. Use of antibiotics especially chloramphenicol and fluroquinolone in animals can lead to antibiotics resistance in intestinal bacteria and it may contribute to increase treatment-resistant illness. The present study was conducted to determine the chloramphenicol and tetracycline residue in fish and prawn by enzyme immunoassay method. A laboratory-based analytical study was carried out from Jan 2011 to Nov 2011 at the Pharmaceutical Toxicology Research Division, DMR (LM). Four species of fish (Japanese threadfin bream, Giant seabass, River shad and Rohu) and two species of prawn (Giant tiger and, Jing) were collected from five markets in Yangon. These samples were extracted and subjected to quantitative analysis of chloramphenicol and tetracycline residues. In four species of fish, the results of chloramphenicol residues ranged from 0.0112 ppb to 0.0776 ppb and 0.025 ppb to 0.0736 ppb for tetracycline. The results in two species of prawn for chloramphenicol ranged from 0.0182 ppb to 0.0206 ppb and 0.019 ppb to 0.028 ppb for tetracycline. According to FAO guideline, the acceptable level for tetracycline is 0.5 ppb and 0.3 ppb for chloramphenicol. Therefore, antibiotics residues in all the samples tested in this study were within acceptable limit.
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