Myanmar Health Sciences Research Journal
Volume 25, Number 2
TITLE: Haematological Manifestations among HIV-TB Co-infected Patients Prior to ART in Specialist Hospital Waibagi and Specialist Hospital Thakayta, Yangon Region, Myanmar.
AUTHOR: Phyu Sin Aye; Sabai Phyu; Myo Myo Mon; Htin Aung Saw
SOURCE: Myanmar Health Sciences Research Journal. 2013; 25(2): 130-135
ABSTRACT: A cross-sectional descriptive study was conducted to find out the typical pattern of haematological manifestations in HIV-TB co-infected patient to assist in diagnosing TB among HIV-infected individuals and to provide baseline haematological data for further studies on HIV-TB co-management. The haematological parameters, namely haemoglobin level, platelet count, total white blood cell count. neutrophil count and lymphocyte count of 77 co-infected patients, who were not yet started antiretroviral therapy, attended to Specialist Hospital Waibagi and Specialist Hospital Thakayta between June 2010 and June 2012 were studied. The haematological abnormalities detected were anaemia (61 cases, 79.2%), thrombocytopenia (13 cases, 16.9%), thrombocytosis (10 cases, 13%), leucopenia (13 cases, 16.9%), leucocytosis (17 cases, 22.1%), neutropenia (5 cases, 6.5%), neutrophilia (21 cases, 27.3%) and lymphopenia (64 cases, 83.1%). There were no cases of lymphocytosis. Among the patients, eight (10.4%) showed bicytopenia and seven (9.1%) had pancytopenia. As lor WBC count abnormalities, the combined presentation of neutrophilia and lymphopenia (24.7%) is the second most predominant feature following lymphopenia alone (54.5%), In conclusion, this study depicted a higher prevalence of anaemia and lymphopenia among HIV-TB co-infection compared to previous studies of HIV infection alone, and it revealed that the presence of thrombocytosis and neutrophilia-lymphopenia combination pattern may imply co-infection with TB.
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