Myanmar Health Sciences Research Journal

Archives   2013

Myanmar   Health   Sciences   Research   Journal

Volume   25,  Number   2

TITLE:   Thiamine Status of Children at a Foster Monastery School in Mayangone Township.
AUTHOR:   Saw Win; Win Lai May; Theingi Thwin; Han Win; Sandar Tun; Nyan Win; Myat Myat Thu; Khin Thidar War; Win Lwin
SOURCE:   Myanmar Health Sciences Research Journal. 2013; 25(2): 125-129
ABSTRACT:   Children in low socioeconomic class with low nutritional status and high carbohydrate intake may be at risk of subclinical thiamine deficiency. A cross-sectional descriptive study was conducted to identify the clinical manifestations of thiamine deficiency, to assess the dietary habit and to determine the thiamine status by red cell transketolase activity in school-age children (5-15 years) at a foster monastery school in Mayangone Township. Fifty boys were recruited into the study. The children were examined to identify the signs and symptoms of thiamine deficiency and blood samples were collected to analyze the red cell transketolase activity. Dietary survey was done by asking the chief cook and the children, and samples of raw and cooked rice were examined for thiamine content. In this study, the WHO recommended cut-off points for percentage of erythrocyte transketolase activity (ETKA) after stimulation were used to assess the thiamine status. There was no association between thiamine status and clinical features of deficiency or dietary thiamine intake. Thiamine content of both raw and cooked rice was found to be adequate comparing with food composition table for use in East Asia. In children, mean value of ETKA after stimulation was 7.77%. Although there was no severe thiamine deficiency, 5(10%) of children still showed marginally deficient in thiamine. This evidence of subclinical thiamine deficiency supports the need for implementation of an effective thiamine supplementation programme to school-age children at foster cares.

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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar