Myanmar Health Sciences Research Journal


Archives   2013

Myanmar   Health   Sciences   Research   Journal

Volume   25,  Number   2

TITLE:   Blood Glucose Lowering Effect of Lagerstrocmia speciosa (L.) Pers. (Banaba) Leafon Rat Model.
AUTHOR:   Khin Phyu Phyu; Lei Lei Win; Mya Mar Lar; Saw Ohnmar Khin; Tin Moe Hlaing; Aye Than
SOURCE:   Myanmar Health Sciences Research Journal. 2013; 25(2): 87-90
ABSTRACT:   The plant Lagerstroemia speciosa L. (Banaba, ysOfr in Myanmar name) was scientifically evaluated for its hpoglycaemic property. Although the plant has been reputed to have this properly, it has not yet been utilized by local people as a remedy for blood glucose lowering effect in diabetes. In the study, 80% ethanolic extract of banaba leaf was tested for the blood glucose lowering effect on adrenaline-induced hyperglycaemia in a rat model. Significant reduction of blood glucose levels were observed, showing maximum effect at 3 hours, at the dose level of 100 mg/kg body weight. Acute toxicity test and physico-chemical studies of the leaf extracts of the plant were also carried out. The acute toxicity studies carried out on mice have not revealed side effects of this extract at the dosages tested up to maximal feasible dose of 8 g/kg. This is the scientific study showing the potential use of banaba leaf in diabetes due to its considerable hypoglycaemic activity.
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