Myanmar Health Sciences Research Journal
Volume 26, Number 3
TITLE: Antihypertensive Effect of Millingtonia hortensis Linn. f. Leaves (Aykayit) on Stage 1 Hypertensive Patients
AUTHOR: Khine Khine Lwin; May Aye Than; Thein Kyaw; Tin Tin Htay; Ko Ko Zaw; Khin Taryar Myint; Nu Nu Win; Win Win Maw
SOURCE: Myanmar Health Sciences Research Journal. 2014; 26(3): 207-213
ABSTRACT: This study was done to determine the antihypertensive effect or Millingtonia hortensis Linn. f. dried leave powder tablet on 16 (Stage I) hypertensive patients attending the Out Patient Department or Traditional 10 Medicine Hospital, Yangon. Study design was open type (single arm) study, after the wash-out period of3 days, the patients were treated orally with dried leaves powder tablet (500 mg). 3 g. three times daily of 4 weeks. Blood pressure was monitored at 0 hr. 0.5 hr and hourly up to 6 hr after the first dose of the trial drug, Monitoring of blood pressure and vital signs were done Oil day I day 2 day 3 and weekly up to 4 week. Side effects were monitored on each patient follow-up. Investigations or biochemical and hematological parameters (blood for complete picture. random blond sugar. Liver Function Test. Renal Function Test) and ECG were done before and at the end (If the study. It was round that significant reduction or the mean supine blood pressure from baseline level was from I hr to3 hrs after the first dose or the trial drug, at the end of the trial. significant reductions in the mean supine systolic and diastolic blood pressures were found from 144.69
SUBJECT HEADINGS: Antihypertensive effect. Millingtonia hortensis Linn. f.