Myanmar Health Sciences Research Journal

Archives   2014

Myanmar   Health   Sciences   Research   Journal

Volume   26,  Number   2

TITLE:   Antibiotic Susceptibility Pattern among Helicobacter pylori Isolates from Chronic Dyspepsia Patients
AUTHOR:   Mya Mya Aye; Thein Myint; Moe Myint Aung; Thuzar Myint; Aye Aye Maw; Haymar Win; Wah Wah Aung
SOURCE:   Myanmar Health Sciences Research Journal. 2014; 26(2):147-152
ABSTRACT:   The importance of H. pylori as an etiological agent in gastroduodenal disease had suggested antibiotic treatment as the main target for the elimination of infection. A cross-sectional, descriptive study was conducted from September 2012 to August 2013 to isolate the H. pylori from chronic dyspepsia patients and also to determine the drug sensitivity profile of isolated H. pylori. Two hundred gastric biopsy specimens were taken from dyspeptic patients comprising 100 gastritis cases and 40 duodenal ulcer cases and 60 gastric ulcer patients. Helicobacter pylori were isolated from 30 cases (15%), comprising 20 cases (20%) of gastritis, 6 cases (10%) of gastric ulcer and 4 cases (10%) of duodenal ulcer. Antibiotic susceptibility profile of isolated H. pylori was determined by using the Epsilometer test (E test). Nineteen (63.3%) of the isolates were resistant to clarithromycin (Minimum Inhibitory Concentration) MICs>256
SUBJECT HEADINGS:   Helicobacter pylori; Dyspepsia; Anti-Bacterial Agents

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Vision : Achieving a healthier nation through application of research findings          Mission Statement : To Develop and promote solutions to the major health problems of Myanmar